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Diazepam is N-demethylated by CYP3A4 and 2C19 towards the Lively metabolite N-desmethyldiazepam, and it is hydroxylated by CYP3A4 on the active metabolite temazepam. N-desmethyldiazepam and temazepam are each further more metabolized to oxazepam. Temazepam and oxazepam are mostly removed by glucuronidation.Psychiatric and paradoxical reactions are

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